Anti -N Cadherin Rabbit pAb

價格：在線咨詢

貨號：

KT011886

產品規(guī)格：

100 μL

Applications：

Species：

HMR

品牌：

萬物

購買數量：

立即詢價在線咨詢 400-1016-218

產品詳情操作說明注意事項

Product Information

Description	N Cadherin rabbit polyclonal antibody
Protein full name	Cadherin-2
Synonyms	Neural cadherin, N-cadherin, CD325, CDw325, Cadherin 2 N cadherin neuronal, CDHN, Cdh2, Cadherin 2 type 1, NCAD, N cadherin 1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse N Cadherin
Isotype	IgG
Purity	Affinity purification
Predicted MW.	100 kDa
Observed MW.	140 kDa
Uniprot ID	P19022, P15116, Q9Z1Y3

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	skeletai muscle, testis

Background

N-cadherin (neuronal cadherin; or CDH2/cadherin 2) is a calcium-binding, single pass transmembrane cell adhesion molecule (CAM) that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail.

Images

Western blot analysis of CDH2 (GB111009) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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