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Product Information
Description |
Presenilin 1 rabbit polyclonal antibody |
Protein full name |
Presenilin-1 |
Synonyms |
PSEN1, Psen1, Ad3h, PS-1, PS1, S182, AD3, FAD, presenilin 1, ACNINV3 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human Presenilin 1 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
53 kDa |
Observed MW. |
22 kDa |
Uniprot ID |
P49768, P49769, P97887 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 1500 | brain, liver, spleen |
Background
Presenilin-1 is one of the four core proteins in the gamma secretase complex, which is considered to play an important role in generation of amyloid beta (Aβ) from amyloid precursor protein (APP). Accumulation of amyloid beta is associated with the onset of Alzheimer's disease.
Images
Western blot analysis of Presenilin1 (GB11779) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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